EA - CE: Announcing our 2023 Charity Ideas. Apply now! by SteveThompson

Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: CE: Announcing our 2023 Charity Ideas. Apply now!, published by SteveThompson on February 13, 2023 on The Effective Altruism Forum.Apply now to start a nonprofit in Biosecurity or Large-Scale Global Health In this post we introduce our top five charity ideas for launch in 2023, in the areas of Biosecurity and Large-Scale Global Health. These are the result of five months’ work from our research team, and a six-stage iterative process that includes collaboration with partners and ideas from within and outside of the EA community.We’re looking for people to launch these ideas through our July - August 2023 Incubation Program. The deadline for applications is March 12, 2023. [APPLY NOW]We provide cost-covered two-month training, stipends, ongoing mentorship, and grants up to $200,000 per project. You can learn more on our website. We also invite you to join our event on February 20, 6PM UK Time. Sam Hilton, our Director of Research, will introduce the ideas and answer your questions. Sign up here.Disclaimers:In an effort to be brief we have sacrificed nuance, the details of our considerable uncertainties, and the downside risks that are discussed in the longer reports; these shall be published in the upcoming weeks.Please note that previous incubatees attest to the ideas becoming increasingly exciting over the course of the program.One-Sentence SummariesAn organization that works to prevent the growth of antimicrobial resistance by advocating for better (pull) funding mechanisms to drive R&D and responsible use of new antibiotics.An advocacy organization that promotes academic guidelines to restrict potentially harmful “dual-use” research.A charity that rolls out dual HIV/syphilis rapid diagnostic tests, penicillin, and training to antenatal clinics, to effectively tackle congenital syphilis at scale in low-and middle-income countries.An organization that distributes Oral Rehydration Solution and zinc co-packages to effectively treat life-threatening diarrhea in under five year olds in low-and middle-income countries.A charity that builds healthcare capacity to provide “Kangaroo Care”, an exceptionally simple and cost-effective treatment, to avert hundreds of thousands of newborn deaths each year in low-and middle-income countries.One-Paragraph Summaries1. Preventing growth of antimicrobial resistance by advocating for better (pull) funding mechanisms to drive R&D and responsible use of new antibioticsAntimicrobial resistance (AMR) is where harmful microbes develop the ability to resist treatment. Recent reports suggest that there are 47 million disability adjusted life years (DALYs) per annum attributed to antibiotic resistance (a key type of AMR). The current financial incentives for new antimicrobial drug development are insufficient, and only a handful of novel antibiotics have been brought to market in the last 30 years. There are well-developed proposals for new market mechanisms using a “subscription” model that would solve this issue. This new charity will advocate for these better market mechanisms, to incentivise the creation and responsible deployment of important new antimicrobial drugs. We estimate that government spending on new market mechanisms for antibiotics could lead to a DALY averted for $100-$150.2. Advocacy for restricting potentially harmful “dual-use” researchDual-use research of concern (DURC) is well-intended research which can lead to harm, either by accident or through deliberate misapplication of the technology. DURC could be a key risk factor for the occurrence of a particularly deadly pandemic during the next 50 years. This risk should be mitigatable with the development and adoption of good practice. We analyzed a dozen case studies of attempts to ensure research safety, ranging from animal testing to human cloning, and w...