Lamotrigine Pharmacology
Real Life Pharmacology - Pharmacology Education for Health Care Professionals - A podcast by Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist - Thursdays
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On this episode of the Real Life Pharmacology podcast, I discuss the ins and outs of lamotrigine pharmacology. Lamotrigine has a very slow dose titration schedule due to the risk of drug induced rash. Sedation, GI upset, and CNS changes are the most common adverse effects associated with lamotrigine. Lamotrigine concentrations can be increased by valproic acid, so we tend to use lower starting doses. Phenytoin and carbamazepine can lower concentrations of lamotrigine.
