Fluticasone Nasal Pharmacology
Real Life Pharmacology - Pharmacology Education for Health Care Professionals - A podcast by Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist - Thursdays
Categories:
Fluticasone (Flonase) is a nasal corticosteroid that is used in the management of allergic rhinitis. A primary adverse effect that I have seen in practice with fluticasone is the risk for nose bleeds. Flonase can have some interactions via CYP3A4. Inhibitors of CYP3A4 like clarithromycin can increase concentrations. While the risk for systemic exposure is low with nasal fluticasone, long-term, high dose, and frequent use should be monitored appropriately.
