Esomeprazole (Nexium) Pharmacology
Real Life Pharmacology - Pharmacology Education for Health Care Professionals - A podcast by Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist - Thursdays
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On this episode, I discuss esomeprazole (Nexium) pharmacology, adverse effects, tapering, kinetics, and drug interactions. I spend a good amount of time discussing the esomeprazole and clopidogrel interaction in this podcast episode. Esomeprazole inhibits CYP2C19. This can cause an increase in citalopram concentrations and raise the potential for QTc prolongation. It is critical to reassess the length of therapy and the dose of PPIs like esomeprazole.
