Codeine Pharmacology
Real Life Pharmacology - Pharmacology Education for Health Care Professionals - A podcast by Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist - Thursdays
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On this episode, I discuss codeine pharmacology and practical clinical practice pearls. Codeine is metabolized by CYP2D6 to the active metabolite morphine. I discuss how this can be affected by genetics as well as other medications. Constipation is a problem with codeine and all opioids in general. Education and making a plan with patients to combat this side effect is important. Codeine is less potent than other opioids such as fentanyl, hydromorphone, and hydrocodone.
