Parmita Mishra — How to Think About Biology (EP.244)

Parmita Mishra is a computational biologist and the founder & CEO of Precigenetics, a company aiming to become a rocket to precision medicine. Parmita is deeply knowledgeable about cutting-edge biology, particularly epigenetics — how behavior and environment can affect gene function without altering genetic code. Her passion for advancing our understanding of diseases is inspiring (and contagious: OSV is an investor in Parmita’s company!) In our conversation, Parmita and I discuss everything from the curious case of male baldness to how her parents have saved 50,000 lives.  I hope you enjoy this conversation as much as I did. For the full transcript, highlights, and bucketloads of other goodies designed to make you go, “Hmm, that’s interesting!”, check out our Substack. Important Links: LinkedIn Twitter Website Precigenetics Twitter Preciginetics launch post Show Notes: Explaining epigenetics to a golden retriever The curious case of male pattern baldness How to think about biology: start from first principles & beware binary thinking The lens you look through determines what you see The problem of data collection in biology Why the FDA needs to change its approach Why we still don’t understand the human brain Garry Tan’s advice: “Get an idea. Get a co-founder.” What’s been surprising about foundership? Failure is a ladder Obsession & how Parmita’s parents have saved 50,000 lives The most surprising things about America Parmita as World Empress Books Mentioned: What is Life?; by Erwin Schrodinger I should have loved biology; by James Somers Gödel, Escher, Bach: An Eternal Golden Braid; by Douglas Hofstadter The Hypomanic Edge: The Link Between (A Little) Craziness and (A Lot of) Success in America; by John D. Gartner