#49: benazepril (Lotensin) | Hypertension Treatment With Benefits in Heart Failure

Benazepril, also known as Lotensin, is an antihypertensive agent. It works by competitively inhibiting the conversion of angiotensin I to angiotensin II. The onset of action is between 1-2 hours. When treating hypertension the treatment range is between 10-40 mg PO qd-bid. When first initiating, start at 10 mg PO qd with a max of 80 mg per day. There is black box warning for fetal toxicity. Common side effects are cough, fatigue, dizziness, hypotension, and hyperuricemia. Benazepril should be stopped ASAP if the patient is pregnant due to risks of fetal injury and fetal death. Sone monitoring parameters are blood pressure, BUN, Cr, electrolytes, and WBCs.After sitting down or lying down for a period of time, avoid getting up to fast to avoid orthostatic hypotension.  Go to DrugCardsDaily.com for episode show notes which consist of the drug summary, quiz, and link to the drug card for FREE! Please SUBSCRIBE, FOLLOW, and RATE on Spotify, Apple Podcasts, or wherever your favorite place to listen to podcasts are. The main goal is to go over the Top 200 Drugs with the occasional drug of interest. Also, if you’d like to say hello, suggest a drug, or leave some feedback I’d really appreciate hearing from you! Leave a voice message at anchor.fm/drugcardsdaily or find me on twitter @drugcardsdaily